Zithromax is an antibiotic, which belongs to a group of medicines called azalides. Zithromax is also used to prevent infections by a bacterium called Mycobacterium Avium-intracellulare Complex in some people. Zithromax is employed to take care of infections in several parts of the body caused by bacteria.
Drug interaction studies were performed with azithromycin and other drugs apt to be co-administered. Co-administration with efavirenz or fluconazole had a modest effect on the pharmacokinetics of azithromycin. No dosage adjustment of either drug is preferred when azithromycin is coadministered with any of these agents.
Essentially, the QT interval measures the depolarization and repolarization that occurs in the heart’s ventricles. QT interval prolongation is associated with decreased heartrate. These prolonged QT intervals can typically be detected using diagnostic machines such as electrocardiogram . Risk factors for Zithromax arrhythmia include preexisting heart conditions.
Because re-infection is common, women and men with gonorrhea should be retested 90 days after treatment of the initial infection, regardless of whether they believe their sex partners were successfully treated. Every effort has been made to ensure that the info provided by Cerner Multum, Inc. (‘Multum’) is accurate, up-to-date, and complete, but no guarantee was created to that effect. Drug information contained herein may be time sensitive. Multum’s drug information does not endorse drugs, diagnose patients or recommend therapy.
500 mg PO once daily for 3 days, or 500 mg PO once daily for 1 day accompanied by 250 mg PO once daily for 4 days. 20 mg/kg/dose PO once weekly as preferred therapy, or alternatively, 5 mg/kg/dose PO once daily. Primary prophylaxis is recommended in infants with a CD4 count significantly less than 750 cells/mm3. Do not discontinue primary prophylaxis for children younger than 2 years. Primary prophylaxis is recommended in children 1 to 2 24 months with a CD4 count less than 500 cells/mm3.
For the 122 patients who have been evaluated at the Day 30 visit, the clinical success rate was 70% for azithromycin. Co-administration of azithromycin at therapeutic doses had a modest effect on the pharmacokinetics of the drugs listed in Table 1. No dosage adjustment of drugs listed in Table 1 is recommended when co-administered with azithromycin.